Cannabidiol (CBD) is one of the hundreds of compounds called cannabinoids that are found in cannabis (hemp & marijuana) plants – with a rich history as a medicine going back thousands of years. You might be thinking, “Isn’t that where marijuana comes from?” Yes, but unlike the mind-altering compound tetrahydrocannabinol (THC), Cannabidiol is non-psychoactive, meaning it will not get you high. Since Cannabidiol does not cause psychoactive effects, it is an excellent option for people seeking the benefits of cannabis products without the high or breaking federal law. Today the therapeutic properties of CBD are being tested and confirmed by scientists and doctors around the world. A safe, non-addictive substance, CBD is one of more than a hundred “phytocannabinoids,” which are unique to cannabis and endow the plant with its robust therapeutic profile.

CBD and THC interact with our bodies in a variety of ways. One of the main ways they impact us is by mimicking and augmenting the effects of the compounds in our bodies called “endogenous cannabinoids” – so named because of their similarity to the compounds found in the cannabis plant. These “endocannabinoids” are part of a regulatory system called the “endocannabinoid system”.

The discovery of the endocannabinoid system has significantly advanced our understanding of health and disease. It has major implications for nearly every area of medical science and helps to explain how and why CBD and THC are such versatile compounds – and why cannabis is such a widely consumed mood-altering plant, despite its illegal status.

The endocannabinoid system plays a crucial role in regulating a broad range of physiological processes that affect our everyday experience – our mood, our energy level, our intestinal fortitude, immune activity, blood pressure, bone density, glucose metabolism, how we experience pain, stress, hunger, and more.

What happens if the endocannabinoid system doesn’t function properly? What are the consequences of a chronically deficient or overactive endocannabinoid system?

In a word, disease.

Cutting-edge science has shown that the endocannabinoid system is dysregulated in nearly all pathological conditions. Thus, it stands to reason that “modulating endocannabinoid system activity may have therapeutic potential in almost all diseases affecting humans,” as Pal Pacher and George Kunos, scientists with the U.S. National Institutes of Health (NIH), suggested in a 2014 publication.

By modulating the endocannabinoid system and enhancing endocannabinoid tone, CBD and THC can slow – or in some cases stop – disease progression.

Yes, CBD is 100% naturally occurring chemical compound that comes directly from the Cannabis plant. It is not synthetically made.

No. Simply put you cannot get high from CBD because it’s a non-intoxicating compound. CBD is actually antagonistic to the THC Marijuanna high. Research shows, CBD doesn’t bind to your brain like the THC molecules, and that is the reason it does not get you high.

A critical review by the World Health Organization (WHO) recently reported that CBD is a promising treatment for a number of medical conditions, is well tolerated, has a good safety profile, and doesn’t appear to be a risk for abuse, dependence, or other public-health related problems. Some of the common known side effects of CBD include nausea, fatigue and irritability. CBD can increase the level in your blood of the blood thinner coumadin, and it can raise levels of certain other medications in your blood by the exact same mechanism that grapefruit juice does. Therefore, if you are on any existing medication, it is best to consult your doctor before using CBD products.

Also, because CBD oil is not yet regulated, it’s up to the consumer to discern between high-quality concentrates and snake oil. As a general rule, we recommend purchasing organic, third-party tested oils sourced from domestically grown cannabis.

Oral ingestion is one of the most popular methods for consuming CBD.  CBD oil is an easy and effective method for consumption because you simply use a dropper to place a few drops under your tongue. Always try to hold the oil under your tongue for at least a minute prior to swallowing. This sublingual method allows for the CBD to bypass your liver and enter your bloodstream at a faster rate.

The perfect dosage is different for everyone, some need more,  others need less. It’s up to you to find your perfect dosage. Generally, we suggest following the product’s recommended serving size for 1 week.  If you feel it is not working for you after that time, increase your dosage until satisfied.            

CBD works differently for different people. As with most nutraceuticals, metabolic factors will affect how you react to CBD, like your age, weight and gender. Also, people are turning to CBD to help with many symptoms, so there’s no general response on how CBD will affect you. Our best advice is to use CBD on a consistent basis to see the best results.

CBD Hemp oil has a very unique composition of nutritional values, which is why we suggest it to everyone. CBD oil contains nutrients that are hard to come by, like terpenes, phytocannabinoids, and other phytonutrients.

Our proprietary blend of compounds, terpenes, and premium grade CBD oil makes us the best choice for your needs. Our products are full-spectrum and made by using premium C02 extraction method which preserves the natural plant terpenes, antioxidants, and neuroprotectants found in hemp. As a result, our formulations deliver high impact wellness products.

The power of hemp is boosted naturally by using more than just CBD compounds in the hemp plant. The full-spectrum of cannabinoids, terpenes, polyphenols, and antioxidants extracted from the plants work together to magnify the therapeutic benefits of each individual cannabinoid. This is commonly referred to as the entourage effect. The entourage effect simply means…You’re getting the entire plant’s goodness.

Cannabidiol or CBD is legal in the U.S. as long as it contains the legal limit of 0.3% or less of THC.

Remember that not all CBD products are created equal. Just as with any industry there are both superior and inferior products on the market. Which is exactly why we decided to create Cannisence, a hemp-based wellness and lifestyle brand for the discerning CBD consumer.

  • Efficacy (This is your CBD quality… Is it full spectrum, CO2 Extracted, Organic Hemp)
  • Lab-results for third party testing (testing to make sure the product is free of pesticides, and solvents. AND to guarantee that what it says on the label is in the bottle .. IS actually in the bottle.

OUR BRAND PROMISE: Here at Cannisnece, We are guided by industry best practices and an unwavering commitment to quality, purity, and safety.

THC carries a psychoactive compound that CBD does not. THC affects the brain by binding to naturally occurring receptors in the central nervous system. CBD is a different shaped molecule that binds to receptors in cell and body tissue outside of the central nervous system. Thus meaning, a user won’t feel a “head high” or a euphoric-like state of mind.

Absolutely. This is a consumer favorite because you can ultimately pair CBD with every meal you make. You can also replace your creamer with CBD oil in your morning cup of coffee.

CBD topicals are great for a number of reasons. Some consumers may have trouble swallowing oils or do not prefer the taste, topicals can be an alternative route. The CBD compound carries many beneficial properties that when combined with a body or muscle cream, can help to support the elimination of many skin issues, minor burns, scrapes, sores, body aches or discomfort.

No, because a topical is applied directly to your skin, it never reaches the bloodstream. It works differently, the CBD is absorbed through your skin and connects to the closest CBD receptors, in your body.

While we cannot say for sure what will be the outcome in the event of a drug test, if a product contains the legal limit of 0.3% or less of THC, it may result in a positive test.

Yes, Cannisence products are sold and shipped to all 50 states.

All packages are sent out by USPS priority mail, for convenience, you will receive an email confirmation with a tracking number.

If you’ve placed an order and would like to modify the items or shipping address, please call our team at 1 (800) 970-4254. If the order has not shipped, we can modify the order for you. If the order has shipped, you will then need to follow the return/exchange process.

Standard exclusions for promotions are as follows:

• Coupons and offers cannot be combined.

At Cannisence, we stand behind our products 100%. We’re certain that our products will become a daily part of your wellness routine and that if any item does not live up to your desires, you can send it back within the initial 30 days of purchase for a refund.

The statements made regarding these products have not been evaluated by the Food and Drug Administration. The efficacy of these products has not been confirmed by FDA-approved research. These products are not intended to diagnose, treat, cure or prevent any disease. All information presented here is not meant as a substitute for or alternative to information from health care practitioners. Please consult your health care professional about potential interactions or other possible complications before using any product. The Federal Food, Drug, and Cosmetic Act require this notice.


Our Chief Medical Officer, Dr. Jose Foradada III, is a renowned pediatric neurosurgeon and has been studying hemp oils and prescribing hemp related products to his patients for years. The products we have selected are based on efficacy, affordability and purity.

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